Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

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第一作者： Daniel C,Scott

第一单位： Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

作者： Daniel C,Scott ^[1] ; Jared T,Hammill ^[2] ; Jaeki,Min ^[3] ; David Y,Rhee ^[3] ; Michele,Connelly ^[4] ; Vladislav O,Sviderskiy ^[3] ; Deepak,Bhasin ^[1] ; Yizhe,Chen ^[3] ; Su-Sien,Ong ^[3] ; Sergio C,Chai ^[3] ; Asli N,Goktug ^[3] ; Guochang,Huang ^[3] ; Julie K,Monda ^[5] ; Jonathan,Low ^[1] ; Ho Shin,Kim ^[3] ; Joao A,Paulo ^[3] ; Joe R,Cannon ^[4] ; Anang A,Shelat ^[4] ; Taosheng,Chen ^[3] ; Ian R,Kelsall ^[3] ; Arno F,Alpi ^[6] ; Vishwajeeth,Pagala ^[7] ; Xusheng,Wang ^[8] ; Junmin,Peng ^[8] ; Bhuvanesh,Singh ^[1] ; J Wade,Harper ^[8] ; Brenda A,Schulman ^[5] ; R Kip,Guy ^[4]

作者单位： Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[1] Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[2] Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[3] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA. ^[4] Laboratory of Epithelial Cancer Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. ^[5] MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK. ^[6] Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany. ^[7] St. Jude Proteomics Facility, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. ^[8]