Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production.
作者:
主题词
血管紧张素Ⅱ(Angiotensin II);动物(Animals);主动脉, 腹(Aorta, Abdominal);主动脉瘤, 腹(Aortic Aneurysm, Abdominal);主动脉破裂(Aortic Rupture);疾病模型, 动物(Disease Models, Animal);细胞外基质(Extracellular Matrix);成纤维细胞(Fibroblasts);牙龈(Gingiva);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);预防和防护用药(Protective Agents);金属蛋白酶1组织抑制剂(Tissue Inhibitor of Metalloproteinase-1);转化生长因子β(Transforming Growth Factor beta)
DOI
10.1093/cvr/cvx110
PMID
28582477
发布时间
2022-03-16
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Cardiovascular research
1364-1375页
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