Chemical Methods to Knock Down the Amyloid Proteins.

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第一作者： Na,Gao

第一单位： Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. gaona_chocolate@126.com.

作者： Na,Gao ^[1] ; Yong-Xiang,Chen ^[2] ; Yu-Fen,Zhao ^[3] ; Yan-Mei,Li ^[4]

作者单位： Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. gaona_chocolate@126.com. ^[1] Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. chen-yx@mail.tsinghua.edu.cn. ^[2] Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. yfzhao@xmu.edu.cn. ^[3] Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China. liym@mail.tsinghua.edu.cn.;Beijing Institute for Brain Disorders, Beijing 100069, China. liym@mail.tsinghua.edu.cn. ^[4]

关键词 amyloid proteins chemical methods degradation

主题词促淀粉样变蛋白质类(Amyloidogenic Proteins);自噬(Autophagy);分子伴侣(Molecular Chaperones);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);蛋白质结合(Protein Binding);构效关系(Structure-Activity Relationship);泛素类(Ubiquitins)

DOI 10.3390/molecules22060916

PMID 28587164

发布时间 2023-09-28

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