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Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation.

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第一作者： Janet L,Oblinger

第一单位： Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University College of Medicine, Columbus, OH, USA.

作者： Janet L,Oblinger ^[1] ; Sarah S,Burns ^[1] ; Jie,Huang ^[1] ; Li,Pan ^[2] ; Yulin,Ren ^[2] ; Rulong,Shen ^[3] ; A Douglas,Kinghorn ^[2] ; D Bradley,Welling ^[4] ; Long-Sheng,Chang ^[5]

作者单位： Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University College of Medicine, Columbus, OH, USA. ^[1] Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University College of Pharmacy, Columbus, OH, USA. ^[2] Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA. ^[3] Department of Otolaryngology-Head and Neck Surgery, The Ohio State University College of Medicine, Columbus, OH, USA. ^[4] Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Otolaryngology-Head and Neck Surgery, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA. Electronic address: Long-Sheng.Chang@nationwidechildrens.org. ^[5]

关键词 Meningioma Merlin Neurofibromatosis type 2 (NF2)Protein translation Silvestrol eIF4A eIF4E eIF4F eIF4G