Evaluation of Small-Animal PET Outcome Measures to Detect Disease Modification Induced by BACE Inhibition in a Transgenic Mouse Model of Alzheimer Disease.
第一作者:
Steven,Deleye
第一单位:
Molecular Imaging Center Antwerp, University of Antwerp, Antwerp, Belgium.
作者:
医学主题词
衰老(Aging);阿尔茨海默病(Alzheimer Disease);淀粉样神经病(Amyloid Neuropathies);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);苯胺化合物(Aniline Compounds);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);脑(Brain);脑化学(Brain Chemistry);酶抑制剂(Enzyme Inhibitors);乙二醇类(Ethylene Glycols);氟脱氧葡萄糖F18(Fluorodeoxyglucose F18);人类(Humans);炎症(Inflammation);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);正电子发射断层显像术(Positron-Emission Tomography);放射性药物(Radiopharmaceuticals);治疗结果(Treatment Outcome)
DOI
10.2967/jnumed.116.187625
PMID
28611242
发布时间
2018-12-19
- 浏览63
Journal of nuclear medicine
1977-1983页
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