TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.
作者:
主题词
动物(Animals);细胞增殖(Cell Proliferation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因, ras(Genes, ras);MAP激酶信号系统(MAP Kinase Signaling System);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);突变(Mutation);NF-κB(NF-kappa B);转化生长因子β(Transforming Growth Factor beta)
DOI
10.1038/cdd.2017.92
PMID
28622298
发布时间
2024-02-10
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Cell death and differentiation
1681-1693页
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