Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia.

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作者： Nilay,Thakkar ^[1] ; Jeffrey T,Guptill ^[2] ; Kathy,Aleš ^[3] ; David,Jacobus ^[3] ; Laura,Jacobus ^[3] ; Charles,Peloquin ^[4] ; Michael,Cohen-Wolkowiez ^[2] ; Daniel,Gonzalez ^[1] ; DAPPER Study Group

作者单位： Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. ^[1] Duke Clinical Research Institute, Durham, North Carolina, USA. ^[2] Jacobus Pharmaceutical Company, Inc., Plainsboro, New Jersey, USA. ^[3] College of Pharmacy and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA. ^[4]

主题词 4-氨基吡啶(4-Aminopyridine);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);芳基胺N-乙酰转移酶(Arylamine N-Acetyltransferase);女(雌)性(Female);人类(Humans);郎伯综合征(Lambert-Eaton Myasthenic Syndrome);下肢(Lower Extremity);男(雄)性(Male);中年人(Middle Aged);模型, 生物学(Models, Biological);肌无力(Muscle Weakness);多态性, 单核苷酸(Polymorphism, Single Nucleotide);钾通道阻滞剂(Potassium Channel Blockers);治疗结果(Treatment Outcome);青年人(Young Adult)

DOI 10.1002/psp4.12218

PMID 28623849

发布时间 2024-06-15

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CPT: pharmacometrics & systems pharmacology

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2017年6卷9期

625-634页

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Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia.

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Population Pharmacokinetics/Pharmacodynamics of 3,4-Diaminopyridine Free Base in Patients With Lambert-Eaton Myasthenia.

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