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Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting.

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第一作者： Jonathan,Pansieri

第一单位： Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Sciences Division, CNRS, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France.

作者： Jonathan,Pansieri ^[1] ; Marie,Plissonneau ^[2] ; Nathalie,Stransky-Heilkron ^[3] ; Mireille,Dumoulin ^[4] ; Laurence,Heinrich-Balard ^[5] ; Pascaline,Rivory ^[5] ; Jean-François,Morfin ^[6] ; Eva,Toth ^[6] ; Maria Joao,Saraiva ^[7] ; Eric,Allémann ^[3] ; Olivier,Tillement ^[8] ; Vincent,Forge ^[1] ; François,Lux ^[8] ; Christel,Marquette ^[1]

作者单位： Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Sciences Division, CNRS, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France. ^[1] Nano-H S.A.S, 38070 Saint Quentin Fallavier, France.;Institut Lumière Matière, University of Lyon, University of Claude Bernard Lyon 1, CNRS, F-69622, Lyon, France. ^[2] School of Pharmaceutical Sciences, University of Geneva, University of Lausanne Pharmaceutical technology, Quai Ernest-Ansermet 30, 1211 Geneva, Switzerland. ^[3] Laboratory of Enzymology & Protein Folding, Centre for Protein Engineering, InBioS, University of Liege Sart Tilman, 4000 Liege, Belgium. ^[4] University of Lyon, University of Claude Bernard Lyon 1, ISPB Faculté de Pharmacie, MATEIS UMR CNRS 5510, 69373 Lyon, France. ^[5] Centre de Biophysique Moléculaire, CNRS, UPR 4301, Université d'Orléans, Rue Charles Sadron, 45071 Orléans, France. ^[6] Instituto de Inovação e Investigação em Saúde (I3S), University of Porto, Portugal; Molecular Neurobiology Group, IBMC - Institute for Molecular & Cell Biology, University of Porto, 4150-180 Porto, Portugal. ^[7] Institut Lumière Matière, University of Lyon, University of Claude Bernard Lyon 1, CNRS, F-69622, Lyon, France. ^[8]

关键词 PIB amyloid imaging amyloidoses gadolinium-based nanoparticles nanobody