Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.-论文-万方医学网

第一作者： Shu,Zhu

第一单位： Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

作者： Shu,Zhu ^[1] ; Siyuan,Ding ^[2] ; Penghua,Wang ^[3] ; Zheng,Wei ^[4] ; Wen,Pan ^[1] ; Noah W,Palm ^[5] ; Yi,Yang ^[1] ; Hua,Yu ^[1] ; Hua-Bing,Li ^[1] ; Geng,Wang ^[1] ; Xuqiu,Lei ^[1] ; Marcel R,de Zoete ^[1] ; Jun,Zhao ^[1] ; Yunjiang,Zheng ^[1] ; Haiwei,Chen ^[6] ; Yujiao,Zhao ^[1] ; Kellie A,Jurado ^[1] ; Ningguo,Feng ^[4] ; Liang,Shan ^[7] ; Yuval,Kluger ^[2] ; Jun,Lu ^[1] ; Clara,Abraham ^[6] ; Erol,Fikrig ^[5] ; Harry B,Greenberg ^[7] ; Richard A,Flavell ^[7]

作者单位： Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. ^[1] Department of Medicine and Department of Microbiology &Immunology, Stanford University School of Medicine, Stanford, California 94305, USA. ^[2] Palo Alto Veterans Institute of Research, VA Palo Alto Health Care System, Palo Alto, California 94304, USA. ^[3] Department of Microbiology and Immunology, New York Medical College, Valhalla, New York 10595, USA. ^[4] Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA. ^[5] Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. ^[6] Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA. ^[7] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA. ^[8]

主题词动物(Animals);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);CARD信号接头蛋白质类(CARD Signaling Adaptor Proteins);半胱氨酸天冬氨酸蛋白酶1(Caspase 1);DEAD-box RNA解旋酶类(DEAD-box RNA Helicases);上皮细胞(Epithelial Cells);女(雌)性(Female);免疫, 先天(Immunity, Innate);炎性体(Inflammasomes);白细胞介素18(Interleukin-18);肠黏膜(Intestinal Mucosa);肠(Intestines);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);磷酸结合蛋白质类(Phosphate-Binding Proteins);RNA, 双链(RNA, Double-Stranded);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);轮状病毒属(Rotavirus);轮状病毒感染(Rotavirus Infections)

DOI 10.1038/nature22967

PMID 28636595

发布时间 2022-05-03

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Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Nature

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Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells.

Nature

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Nature

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