Glucuronidation of deoxynivalenol (DON) by different animal species: identification of iso-DON glucuronides and iso-deepoxy-DON glucuronides as novel DON metabolites in pigs, rats, mice, and cows.

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第一作者： Heidi E,Schwartz-Zimmermann

第一单位： Christian Doppler Laboratory for Mycotoxin Metabolism, Department of Agrobiotechnology (IFA-Tulln), Center for Analytical Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad-Lorenz-Str. 20, 3430, Tulln, Austria. heidi.schwartz@boku.ac.at.

作者： Heidi E,Schwartz-Zimmermann ^[1] ; Christian,Hametner ^[2] ; Veronika,Nagl ^[3] ; Iris,Fiby ^[4] ; Lukas,Macheiner ^[3] ; Janine,Winkler ^[3] ; Sven,Dänicke ^[5] ; Erica,Clark ^[5] ; James J,Pestka ^[6] ; Franz,Berthiller ^[6]

作者单位： Christian Doppler Laboratory for Mycotoxin Metabolism, Department of Agrobiotechnology (IFA-Tulln), Center for Analytical Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad-Lorenz-Str. 20, 3430, Tulln, Austria. heidi.schwartz@boku.ac.at. ^[1] Institute of Applied Synthetic Chemistry, Vienna University of Technology, Getreidemarkt 9/163-OC, 1060, Vienna, Austria. ^[2] Christian Doppler Laboratory for Mycotoxin Metabolism, Department of Agrobiotechnology (IFA-Tulln), Center for Analytical Chemistry, University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad-Lorenz-Str. 20, 3430, Tulln, Austria. ^[3] BIOMIN Research Center, Technopark 1, 3430, Tulln, Austria. ^[4] Institute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute for Animal Health, 38116, Brunswick, Germany. ^[5] Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, 48824, USA. ^[6]

关键词 Cyclic hemiketal DON 8-O-β-D-glucuronide High-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS)Iso-deepoxy-deoxynivalenol Iso-deoxynivalenol Metabolism