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Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study.

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第一作者： Luis,de la Cruz-Merino

第一单位： Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41071, Seville, Spain. lucme12@yahoo.es.

作者： Luis,de la Cruz-Merino ^[1] ; Lorenza,Di Guardo ^[2] ; Jean-Jacques,Grob ^[3] ; Alfredo,Venosa ^[4] ; James,Larkin ^[5] ; Grant A,McArthur ^[6] ; Antoni,Ribas ^[7] ; Paolo A,Ascierto ^[8] ; Jeffrey T R,Evans ^[9] ; Antonio,Gomez-Escobar ^[10] ; Giulio,Barteselli ^[11] ; Susan,Eng ^[11] ; Jessie J,Hsu ^[11] ; Anne,Uyei ^[11] ; Brigitte,Dréno ^[12]

作者单位： Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41071, Seville, Spain. lucme12@yahoo.es. ^[1] Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. ^[2] Aix-Marseille University, Hôpital de la Timone, Marseille, France. ^[3] Ospedale Monaldi, Naples, Italy. ^[4] Royal Marsden NHS Foundation Trust, London, UK. ^[5] Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.;University of Melbourne, Parkville, VIC, Australia. ^[6] Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, CA, USA. ^[7] Istituto Nazionale Tumori Fondazione G. Pascale, Naples, Italy. ^[8] Beatson West of Scotland Cancer Centre, University of Glasgow, Glasgow, UK. ^[9] Servicio de Oncología Médica, Hospital Universitario Virgen Macarena, Avenida Doctor Fedriani 3, 41071, Seville, Spain. ^[10] Genentech, Inc., South San Francisco, CA, USA. ^[11] Nantes University, Nantes, France. ^[12]

关键词 Cobimetinib MEK inhibition Melanoma Serous retinopathy Visual disturbance