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首页> Steroids> The synthesis and antitumor activity of lithocholic acid and its derivatives.

The synthesis and antitumor activity of lithocholic acid and its derivatives.

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作者： Xiao-Long,He ^[1] ; Yajing,Xing ^[2] ; Xiang-Zhong,Gu ^[3] ; Jie-Xin,Xiao ^[1] ; Ying-Ying,Wang ^[1] ; Zhengfang,Yi ^[2] ; Wen-Wei,Qiu ^[4]

作者单位： Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Chemical Engineering, East China Normal University, Shanghai 200241, China. ^[1] Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China. ^[2] Department of Research and Development, Jiangsu Jiaerke Pharmaceuticals Group Co Ltd., Zhenglu Town, Changzhou 213111, China. ^[3] Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Chemical Engineering, East China Normal University, Shanghai 200241, China. Electronic address: wwqiu@chem.ecnu.edu.cn. ^[4]

关键词 Antitumor Apoptosis Breast cancer Lithocholic acid Migration

主题词抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);石胆酸(Lithocholic Acid);构效关系(Structure-Activity Relationship)

DOI 10.1016/j.steroids.2017.06.009

PMID 28648585

发布时间 2018-03-29

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