T-type Ca<sup>2+</sup> channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

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第一作者： Safietou,Sankhe

第一单位： INSERM U999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; Univ. Paris-Sud, Faculté de Médecine, Univ. Paris-Saclay, Le Kremlin Bicêtre, France.

作者： Safietou,Sankhe ^[1] ; Sevasti,Manousakidi ^[1] ; Fabrice,Antigny ^[1] ; Jennifer,Arthur Ataam ^[1] ; Sana,Bentebbal ^[2] ; Yann,Ruchon ^[1] ; Florence,Lecerf ^[1] ; Jessica,Sabourin ^[3] ; Laura,Price ^[4] ; Elie,Fadel ^[1] ; Peter,Dorfmüller ^[1] ; Saadia,Eddahibi ^[2] ; Marc,Humbert ^[5] ; Frédéric,Perros ^[1] ; Véronique,Capuano ^[6]

作者单位： INSERM U999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; Univ. Paris-Sud, Faculté de Médecine, Univ. Paris-Saclay, Le Kremlin Bicêtre, France. ^[1] PhyMedExp, Univ. Montpellier, Inserm U1046, cNRS UMR9214.34295 MINSERM U1046, Montpellier, France. ^[2] INSERM UMR-S1180, Univ. Paris-Sud, Université Paris-Saclay, 92296 Châtenay-Malabry, France. ^[3] National Pulmonary Hypertension Service, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK. ^[4] INSERM U999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; Univ. Paris-Sud, Faculté de Médecine, Univ. Paris-Saclay, Le Kremlin Bicêtre, France; AP-HP, Service de pneumologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France. ^[5] INSERM U999, Hôpital Marie Lannelongue, Le Plessis Robinson, France; Univ. Paris-Sud, Faculté de Médecine, Univ. Paris-Saclay, Le Kremlin Bicêtre, France. Electronic address: veronique.capuano@u-psud.fr. ^[6]

关键词 Caspase Cell cycle FoxO3A Lung MAPkinase Survivin

主题词细胞凋亡(Apoptosis);苯乙酰胺类(Benzeneacetamides);钙通道, T型(Calcium Channels, T-Type);细胞增殖(Cell Proliferation);基因表达调控(Gene Expression Regulation);人类(Humans);肌细胞, 平滑肌(Myocytes, Smooth Muscle);蛋白质磷酸酶2(Protein Phosphatase 2);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);肺动脉(Pulmonary Artery);吡啶类(Pyridines);信号传导(Signal Transduction)

DOI 10.1016/j.bbamcr.2017.06.018

PMID 28655554

发布时间 2018-09-19

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Biochimica et biophysica acta. Molecular cell research

2017年1864卷10期

1631-1641页

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T-type Ca<sup>2+</sup> channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

Biochimica et biophysica acta. Molecular cell research

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Biochimica et biophysica acta. Molecular cell research

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T-type Ca<sup>2+</sup> channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

Biochimica et biophysica acta. Molecular cell research

相似文献

Biochimica et biophysica acta. Molecular cell research

相关期刊

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