Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples.

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第一作者： Nhat Trung,Doan

第一单位： NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway. Electronic address: n.t.doan@medisin.uio.no.

作者： Nhat Trung,Doan ^[1] ; Andreas,Engvig ^[2] ; Krystal,Zaske ^[3] ; Karin,Persson ^[4] ; Martina Jonette,Lund ^[3] ; Tobias,Kaufmann ^[3] ; Aldo,Cordova-Palomera ^[3] ; Dag,Alnæs ^[3] ; Torgeir,Moberget ^[3] ; Anne,Brækhus ^[4] ; Maria Lage,Barca ^[4] ; Jan Egil,Nordvik ^[5] ; Knut,Engedal ^[4] ; Ingrid,Agartz ^[6] ; Geir,Selbæk ^[7] ; Ole A,Andreassen ^[3] ; Lars T,Westlye ^[8] ; Alzheimer's Disease Neuroimaging Initiative

作者单位： NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway. Electronic address: n.t.doan@medisin.uio.no. ^[1] NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway; Department of Medicine, Diakonhjemmet Hospital, Oslo, Norway. ^[2] NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway. ^[3] Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway; Department of Geriatric Medicine, The Memory Clinic, Oslo University Hospital, Oslo, Norway. ^[4] Sunnaas Rehabilitation Hospital HT, Nesodden, Norway. ^[5] NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway; Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway. ^[6] Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway; Centre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway. ^[7] NORMENT, KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Norway; Department of Psychology, University of Oslo, Oslo, Norway. ^[8]

关键词 Alzheimer's disease Alzheimer's disease spectrum Early and late aging Linked independent component analysis Machine learning