换一批Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
第一作者：
Sushant K,Shrivastava
第一单位：
Pharmaceutical Chemistry Research Laboratory, Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi 221005, U.P., India. Electronic address: skshrivastava.phe@itbhu.ac.in.
作者：
主题词
动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);花生四烯酸(Arachidonic Acid);角叉菜胶(Carrageenan);环加氧酶抑制药(Cyclooxygenase Inhibitors);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物设计(Drug Design);水肿(Edema);女(雌)性(Female);吲哚嗪类(Indolizines);脂氧合酶(Lipoxygenase);脂氧合酶抑制剂(Lipoxygenase Inhibitors);男(雄)性(Male);小鼠(Mice);分子结构(Molecular Structure);前列腺素内过氧化物合酶类(Prostaglandin-Endoperoxide Synthases);大鼠(Rats);构效关系(Structure-Activity Relationship);溃疡(Ulcer)
DOI
10.1016/j.bmc.2017.06.027
PMID
28669741
发布时间
2017-12-08
- 浏览9
Bioorganic & medicinal chemistry
4424-4432页
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