Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4.

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作者： Megumi,Tsukamoto ^[1] ; Shiori,Sato ^[2] ; Kazuhiro,Satake ^[3] ; Mizuki,Miyake ^[4] ; Hiroshi,Nakagawa ^[5]

作者单位： Department of Applied Biological Chemistry, Graduate School of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai 487-8501, Japan. gr16801@isc.chubu.ac.jp. ^[1] Department of Applied Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan. ksatake@isc.chubu.ac.jp. ^[2] Department of Applied Biological Chemistry, Graduate School of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai 487-8501, Japan. gr15020@isc.chubu.ac.jp. ^[3] Department of Applied Biological Chemistry, Graduate School of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai 487-8501, Japan. fr14042-0218@sti.chubu.ac.jp. ^[4] Department of Applied Biological Chemistry, College of Bioscience and Biotechnology, Chubu University, 1200 Matsumoto-cho, Kasugai, Aichi 487-8501, Japan. hnakagaw@isc.chubu.ac.jp. ^[5]

关键词 ATP-binding cassette (ABC) transporter ATP-binding cassette subfamily C member 4 (ABCC4)drug resistance multi drug resistance protein 4 (MRP4)single-nucleotide polymorphism (SNP)