Formononetin, a methoxy isoflavone, enhances bone regeneration in a mouse model of cortical bone defect.
第一作者:
Krishna Bhan,Singh
第一单位:
1Division of Endocrinology,Central Drug Research Institute (Council of Scientific and Industrial Research),Sector 10,Jankipuram Extension,Sitapur Road,Lucknow 226031,Uttar Pradesh,India.
作者:
关键词
BMP2
bone morphogenetic protein 2
OCN
osteocalcin
RUNX2
runt-related transcription factor 2 BV/TV trabecular bone volume DA degree of anisotropy DAPI 4’ OVx ovariectomised PTH parathyroid hormone SMI structure model index Tb.N trabecular number Tb.Pf trabecular pattern factor Tb.Th trabecular thickness6-diamidino-2-phenylindoleBone healingBone regenerationFormononetinMicrocomputed tomographyOsteoporosisParathyroid hormone
医学主题词
动物(Animals);骨再生(Bone Regeneration);核心结合因子α1亚基(Core Binding Factor Alpha 1 Subunit);疾病模型, 动物(Disease Models, Animal);豆科(Fabaceae);股骨(Femur);骨折(Fractures, Bone);异黄酮类(Isoflavones);小鼠, 近交BALB C(Mice, Inbred BALB C);骨钙素(Osteocalcin);骨生成(Osteogenesis);卵巢切除术(Ovariectomy);甲状旁腺素(Parathyroid Hormone);植物雌激素类(Phytoestrogens);植物药疗法(Phytotherapy);植物提取物(Plant Extracts);伤口愈合(Wound Healing)
DOI
10.1017/S0007114517001556
PMID
28689509
发布时间
2017-07-31
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The British journal of nutrition
1511-1522页
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