A fusion protein of interleukin-4 and interleukin-10 protects against blood-induced cartilage damage in vitro and in vivo.-论文-万方医学网

作者： L F D,van Vulpen ^[1] ; J,Popov-Celeketic ^[2] ; M E R,van Meegeren ^[2] ; K,Coeleveld ^[1] ; J M,van Laar ^[2] ; C E,Hack ^[2] ; R E G,Schutgens ^[2] ; S C,Mastbergen ^[2] ; F P J G,Lafeber ^[3]

作者单位： Van Creveldkliniek, University Medical Center Utrecht, Utrecht, the Netherlands. ^[1] Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, the Netherlands. ^[2] Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, the Netherlands. ^[3]

主题词老年人(Aged);动物(Animals);软骨, 关节(Cartilage, Articular);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);因子Ⅷ(Factor VIII);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);关节积血(Hemarthrosis);血友病A(Hemophilia A);人类(Humans);炎症介导素类(Inflammation Mediators);白细胞介素10(Interleukin-10);白细胞介素1β(Interleukin-1beta);白细胞介素4(Interleukin-4);白细胞介素6(Interleukin-6);男(雄)性(Male);小鼠, 基因敲除(Mice, Knockout);中年人(Middle Aged);表型(Phenotype);蛋白聚糖类(Proteoglycans);重组融合蛋白质类(Recombinant Fusion Proteins);时间因素(Time Factors);组织培养技术(Tissue Culture Techniques)

DOI 10.1111/jth.13778

PMID 28696534

发布时间 2023-08-29

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A fusion protein of interleukin-4 and interleukin-10 protects against blood-induced cartilage damage in vitro and in vivo.

Journal of thrombosis and haemostasis

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Journal of thrombosis and haemostasis

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A fusion protein of interleukin-4 and interleukin-10 protects against blood-induced cartilage damage in vitro and in vivo.

Journal of thrombosis and haemostasis

相似文献

Journal of thrombosis and haemostasis

相关期刊

检索历史清除