Antibodies to Signaling Molecules and Receptors in Alzheimer's Disease are Associated with Psychomotor Slowing, Depression, and Poor Visuospatial Function.

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作者： Lasse M,Giil ^[1] ; Christian A,Vedeler ^[2] ; Einar K,Kristoffersen ^[3] ; Jan Erik,Nordrehaug ^[4] ; Harald,Heidecke ^[2] ; Ralf,Dechend ^[5] ; Kai,Schulze-Forster ^[2] ; Dominik N,Muller ^[6] ; Victoria S,von Goetze ^[7] ; Otavio,Cabral-Marques ^[8] ; Gabriela,Riemekasten ^[9] ; Petra,Vogelsang ^[7] ; Staale,Nygaard ^[8] ; Anders,Lund ^[10] ; Dag,Aarsland ^[7]

作者单位： Department of Internal Medicine, Haraldsplass Deaconess Hospital, Bergen, Norway. ^[1] Department of Clinical Science, University of Bergen, Bergen, Norway. ^[2] Department of Clinical Medicine, University of Bergen, Bergen, Norway. ^[3] Department of Neurology, Haukeland University Hospital, Bergen, Norway. ^[4] Department of Immunology and Transfusion Medicine, Haukeland University Hospital, Bergen, Norway. ^[5] Department of Cardiology, Stavanger University Hospital, Stavanger, Norway. ^[6] CellTrend GmbH, Luckenwalde, Berlin, Germany. ^[7] Experimental and Clinical Research Center, Charité Medical Faculty and the Max-Delbruck Center for Molecular Medicine, Berlin, Germany. ^[8] HELIOS-Klinikum Berlin, Berlin, Germany. ^[9] Max-Delbruck Center for Molecular Medicine, Berlin, Germany. ^[10] Department of Rheumatology, University Hospital Schleswig-Holstein, Lübeck, Germany. ^[11] Research Group for Biomedical Informatics, University of Oslo, Oslo, Norway. ^[12] Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, Kings College, UK. ^[13] Centre for Age-Related Diseases (SESAM), Stavanger University Hospital, Norway. ^[14]

关键词 5-HT2AR 5-HT2CR 5-HT7R C5aR MADRS Stablin-1 Trail Making A VEGFR1 VOSP naturally occurring antibodies