Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study.

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第一作者： Mahesh,Iddawela

第一单位： Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. mahesh.iddawela@monash.edu.

作者： Mahesh,Iddawela ^[1] ; Oscar,Rueda ^[2] ; Jenny,Eremin ^[3] ; Oleg,Eremin ^[4] ; Jed,Cowley ^[5] ; Helena M,Earl ^[6] ; Carlos,Caldas ^[7]

作者单位： Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. mahesh.iddawela@monash.edu. ^[1] Department of Oncology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK. mahesh.iddawela@monash.edu. ^[2] Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, NIHR Cambridge Biomedical Research Centre and Cambridge Experimental Cancer Medicine Centre, Cambridge, UK. mahesh.iddawela@monash.edu. ^[3] Department of Anatomy & Developmental Biology, Monash University, Clayton, VIC, 3800, Australia. mahesh.iddawela@monash.edu. ^[4] School of Clinical Sciences, Monash University, Clayton, Australia. mahesh.iddawela@monash.edu. ^[5] Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. ^[6] Research and Development, Lincoln Breast Unit, Lincoln County Hospital, Lincoln, UK. ^[7] Nottingham Digestive Disease Centre, Faculty of Medicine and Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK. ^[8] PathLinks, Lincoln County Hospital, Lincoln, UK. ^[9] Department of Oncology, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, UK. ^[10] Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, NIHR Cambridge Biomedical Research Centre and Cambridge Experimental Cancer Medicine Centre, Cambridge, UK. ^[11]

关键词 Breast Cancer Copy Number DASL FFPE Gene Expression Genomics Molecular Inversion Probes Assay Molecular Markers Oncoscan Array