首页> Journal of medicinal chemistry> Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure.

Design, Synthesis, and Evaluation of the Highly Selective and Potent G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitor for the Potential Treatment of Heart Failure.

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第一作者： Tomohiro,Okawa

第一单位： Shonan Research Center, Pharmaceutical Research Division, Takeda Pharmaceutical Co., Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan.

作者： Tomohiro,Okawa ^[1] ; Yoshio,Aramaki ^[1] ; Mitsuo,Yamamoto ^[1] ; Toshitake,Kobayashi ^[1] ; Shoji,Fukumoto ^[1] ; Yukio,Toyoda ^[1] ; Tsutomu,Henta ^[1] ; Akito,Hata ^[1] ; Shota,Ikeda ^[1] ; Manami,Kaneko ^[1] ; Isaac D,Hoffman ^[2] ; Bi-Ching,Sang ^[2] ; Hua,Zou ^[2] ; Tetsuji,Kawamoto ^[1]

作者单位： Shonan Research Center, Pharmaceutical Research Division, Takeda Pharmaceutical Co., Ltd. , 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan. ^[1] Takeda California , 10410 Science Center Drive, San Diego, California 92121, United States. ^[2]