An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells.-论文-万方医学网

作者： Anthony J,St Leger ^[1] ; Jigar V,Desai ^[2] ; Rebecca A,Drummond ^[2] ; Abirami,Kugadas ^[3] ; Fatimah,Almaghrabi ^[1] ; Phyllis,Silver ^[1] ; Kumarkrishna,Raychaudhuri ^[1] ; Mihaela,Gadjeva ^[3] ; Yoichiro,Iwakura ^[4] ; Michail S,Lionakis ^[2] ; Rachel R,Caspi ^[5]

作者单位： Laboratory of Immunology, National Eye Institute, NIH, Bethesda, MD 20892, USA. ^[1] Fungal Pathogenesis Unit, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892, USA. ^[2] Department of Medicine, Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[3] Center for Experimental Animal Models, Institute for Medical Sciences, Tokyo University of Science, Tokyo, Japan. ^[4] Laboratory of Immunology, National Eye Institute, NIH, Bethesda, MD 20892, USA. Electronic address: caspir@mail.nih.gov. ^[5]

主题词动物(Animals);白色念珠菌(Candida albicans);念珠菌病(Candidiasis);角膜(Cornea);棒杆菌属(Corynebacterium);棒杆菌感染(Corynebacterium Infections);疾病模型, 动物(Disease Models, Animal);眼感染(Eye Infections);宿主与病原体相互作用(Host-Pathogen Interactions);人类(Humans);免疫, 黏膜(Immunity, Mucosal);白细胞介素17(Interleukin-17);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);中性白细胞浸润(Neutrophil Infiltration);中性白细胞(Neutrophils);假单胞菌感染(Pseudomonas Infections);铜绿假单胞菌(Pseudomonas aeruginosa);受体, 抗原, T细胞, γ-δ(Receptors, Antigen, T-Cell, gamma-delta);T淋巴细胞(T-Lymphocytes);眼泪(Tears)

DOI 10.1016/j.immuni.2017.06.014

PMID 28709803

发布时间 2020-12-09

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An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells.

Immunity

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An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T Cells.

Immunity

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Immunity

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