A methoxyflavanone derivative from the Asian medicinal herb (Perilla frutescens) induces p53-mediated G<sub>2</sub>/M cell cycle arrest and apoptosis in A549 human lung adenocarcinoma.

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作者： Amer Ali,Abd El-Hafeez ^[1] ; Takashi,Fujimura ^[1] ; Rikiya,Kamei ^[1] ; Noriko,Hirakawa ^[2] ; Kenji,Baba ^[2] ; Kazuhisa,Ono ^[1] ; Seiji,Kawamoto ^[3]

作者单位： Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, 739-8530, Japan. ^[1] Mishima Food Co. Ltd, Hiroshima, Japan. ^[2] Department of Food Sciences and Biotechnology, Faculty of Life Sciences, Hiroshima Institute of Technology, Hiroshima, Japan. ^[3] Hiroshima Research Center for Healthy Aging (HiHA), Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, 739-8530, Japan. skawa@hiroshima-u.ac.jp. ^[4]

关键词 Apoptosis Flavanone G2/M cell cycle arrest Lung cancer Perilla frutescens p53

DOI 10.1007/s10616-017-0116-1

PMID 28710570

发布时间 2019-11-20

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