CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.
第一作者:
Molly,Gasperini
第一单位:
Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA. Electronic address: gasperim@uw.edu.
作者:
医学主题词
细胞系(Cell Line);基因表达调控(Gene Expression Regulation);HEK293细胞(HEK293 Cells);人类(Humans);次黄嘌呤磷酸核糖转移酶(Hypoxanthine Phosphoribosyltransferase);莱施-奈恩综合征(Lesch-Nyhan Syndrome);调控序列, 核酸(Regulatory Sequences, Nucleic Acid);序列缺失(Sequence Deletion);硫鸟嘌呤(Thioguanine)
DOI
10.1016/j.ajhg.2017.06.010
PMID
28712454
发布时间
2024-01-04
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