Development of Three Orthogonal Assays Suitable for the Identification and Qualification of PIKfyve Inhibitors.
第一作者:
Kylie,Fogarty
第一单位:
1 Department of Small Molecule Discovery Research, Boehringer Ingelheim Pharmaceuticals, Inc. , Ridgefield, Connecticut.
作者:
医学主题词
氨基吡啶类(Aminopyridines);动物(Animals);剂量效应关系, 药物(Dose-Response Relationship, Drug);电泳, 凝胶, 脉冲场(Electrophoresis, Gel, Pulsed-Field);酶抑制剂(Enzyme Inhibitors);HEK293细胞(HEK293 Cells);杂环化合物, 3环(Heterocyclic Compounds, 3-Ring);人类(Humans);微流体分析技术(Microfluidic Analytical Techniques);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷脂酰肌醇磷酸盐类(Phosphatidylinositol Phosphates)
DOI
10.1089/adt.2017.790
PMID
28723271
发布时间
2019-12-10
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