Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease.-论文-万方医学网

作者： Velmarini,Vasquez ^[1] ; Joy,Mitra ^[2] ; Pavana M,Hegde ^[3] ; Arvind,Pandey ^[1] ; Shiladitya,Sengupta ^[1] ; Sankar,Mitra ^[1] ; K S,Rao ^[1] ; Muralidhar L,Hegde ^[4]

作者单位： Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX, USA. ^[1] Centre for Neuroscience, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología, City of Knowledge, Republic of Panama. ^[2] Department of Biotechnology, Acharya Nagarjuna University, Guntur, India. ^[3] Weill Cornell Medical College of Cornell University, NY, USA. ^[4] Houston Methodist Neurological Institute, Institute of Academic Medicine, Houston Methodist Hospital, Houston, TX, USA. ^[5]

主题词膜联蛋白A5(Annexin A5);细胞死亡(Cell Death);细胞系, 肿瘤(Cell Line, Tumor);细胞核仁(Cell Nucleolus);染色质(Chromatin);彗星试验(Comet Assay);硫酸铜(Copper Sulfate);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA损伤(DNA Damage);基因表达调控(Gene Expression Regulation);人类(Humans);铁(Iron);神经干细胞(Neural Stem Cells);神经母细胞瘤(Neuroblastoma);神经元(Neurons);氧化还原(Oxidation-Reduction);蛋白质结合(Protein Binding);活性氧(Reactive Oxygen Species);硫化物(Sulfides);α突触核蛋白(alpha-Synuclein)

DOI 10.3233/JAD-170342

PMID 28731447

发布时间 2024-06-10

检索历史清除

Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease.

Journal of Alzheimer's disease

相似文献

Journal of Alzheimer's disease

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease.

Journal of Alzheimer's disease

相似文献

Journal of Alzheimer's disease

相关期刊

检索历史清除