Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia.

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作者： Anne,Benard-Slagter ^[1] ; Ilse,Zondervan ^[1] ; Karel,de Groot ^[2] ; Farzaneh,Ghazavi ^[3] ; Virinder,Sarhadi ^[4] ; Pieter,Van Vlierberghe ^[5] ; Barbara,De Moerloose ^[6] ; Claire,Schwab ^[7] ; Kim,Vettenranta ^[8] ; Christine J,Harrison ^[7] ; Sakari,Knuutila ^[4] ; Jan,Schouten ^[2] ; Tim,Lammens ^[6] ; Suvi,Savola ^[9]

作者单位： Department of Tumour Diagnostics, MRC-Holland, Amsterdam, the Netherlands. ^[1] Research and Development Department, MRC-Holland, Amsterdam, the Netherlands. ^[2] Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium. ^[3] Department of Pathology, University of Helsinki, Faculty of Medicine, Helsinki, Finland. ^[4] Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent, Ghent, Belgium. ^[5] Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium; Cancer Research Institute Ghent, Ghent, Belgium. ^[6] Leukaemia Research Cytogenetics Group, Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom. ^[7] Division of Hematology-Oncology and Stem Cell Transplantation, Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland. ^[8] Department of Tumour Diagnostics, MRC-Holland, Amsterdam, the Netherlands. Electronic address: s.savola@mlpa.com. ^[9]