Endogenous Biomarkers to Assess Drug-Drug Interactions by Drug Transporters and Enzymes.

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第一作者： T Thanga,Mariappan

第一单位： Pharmaceutical Candidate Optimization, Biocon Bristol Myers-Squibb R&D Centre (BBRC), Syngene International Limited, Bangalore - 560 099. India.

作者： T Thanga,Mariappan ^[1] ; Hong,Shen ^[2] ; Punit,Marathe ^[2]

作者单位： Pharmaceutical Candidate Optimization, Biocon Bristol Myers-Squibb R&D Centre (BBRC), Syngene International Limited, Bangalore - 560 099. India. ^[1] Pharmaceutical Candidate Optimization, Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Pennington, NJ 08534. United States. ^[2]

关键词 Endogenous biomarkers drug-drug interactions enzymes induction inhibition transporters

主题词动物(Animals);生物转运(Biological Transport);药物相互作用(Drug Interactions);人类(Humans);膜转运蛋白质类(Membrane Transport Proteins)

DOI 10.2174/1389200218666170724110818

PMID 28738769

发布时间 2018-09-10

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