首页> Journal of molecular and cellular cardiology> D242N, a KV7.1 LQTS mutation uncovers a key residue for IKs voltage dependence.

D242N, a KV7.1 LQTS mutation uncovers a key residue for IKs voltage dependence.

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第一作者： Cristina,Moreno

第一单位： Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.

作者： Cristina,Moreno ^[1] ; Anna,Oliveras ^[2] ; Chiara,Bartolucci ^[3] ; Carmen,Muñoz ^[4] ; Alicia,de la Cruz ^[1] ; Diego A,Peraza ^[1] ; Juan R,Gimeno ^[4] ; Mercedes,Martín-Martínez ^[5] ; Stefano,Severi ^[3] ; Antonio,Felipe ^[2] ; Pier D,Lambiase ^[6] ; Teresa,Gonzalez ^[7] ; Carmen,Valenzuela ^[8]

作者单位： Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain. ^[1] Molecular Physiology Laboratory, Dpt. de Bioquímica i Biologia Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Spain. ^[2] Computational Physiopathology Unit, Dpt. of Electrical, Electronic and Information Engineering "Guglielmo Marconi", University of Bologna, Italy. ^[3] Dpt. of Cardiology, Hospital Universitario Virgen de la Arrixaca de Murcia, Spain. ^[4] Instituto de Química Médica CSIC, Madrid, Spain. ^[5] Dpt. of Cardiac Electrophysiology, The Heart Hospital, Institute of Cardiovascular Science, University College London, London, UK. ^[6] Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain. Electronic address: tgonzalez@iib.uam.es. ^[7] Instituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain. Electronic address: cvalenzuela@iib.uam.es. ^[8]

关键词 Electrophysiology K(V)7.1 KCNE1 Long QT syndrome