PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.

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第一作者： Slim,Mzoughi

第一单位： Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.

作者： Slim,Mzoughi ^[1] ; Jingxian,Zhang ^[2] ; Delphine,Hequet ^[1] ; Shun Xie,Teo ^[1] ; Haitong,Fang ^[1] ; Qiao Rui,Xing ^[3] ; Marco,Bezzi ^[3] ; Michelle Kay Yi,Seah ^[4] ; Sheena L M,Ong ^[1] ; Eun Myoung,Shin ^[2] ; Heike,Wollmann ^[5] ; Esther S M,Wong ^[6] ; Muthafar,Al-Haddawi ^[7] ; Colin L,Stewart ^[8] ; Vinay,Tergaonkar ^[9] ; Yuin-Han,Loh ^[6] ; N Ray,Dunn ^[10] ; Daniel M,Messerschmidt ^[6] ; Ernesto,Guccione ^[2]

作者单位： Methyltransferases in Development and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. ^[1] Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ^[2] Epigenetics and Cell Fates Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. ^[3] School of Biological Sciences, Nanyang Technological University, Singapore. ^[4] Developmental Epigenetics and Disease Group, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. ^[5] Institute of Medical Biology (IMB), Agency for Science, Technology and Research (A*STAR), Singapore. ^[6] Cancer Science Institute of Singapore (CSI), National University of Singapore, Singapore. ^[7] NF-κB Signaling in Human Ailments, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. ^[8] DNA Sequencing Facility NGS Unit, Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. ^[9] Advanced Molecular Pathology Laboratory, IMCB, Singapore. ^[10] National Cancer Centre Singapore, Singapore. ^[11] Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia. ^[12] Department of Biological Sciences, National University of Singapore, Singapore. ^[13] Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA. ^[14]