A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1.

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作者： Nikki,Buijs ^[1] ; J Efraim,Oosterink ^[2] ; Morgan,Jessup ^[3] ; Henk,Schierbeek ^[4] ; Donna B,Stolz ^[5] ; Alexander P,Houdijk ^[4] ; David A,Geller ^[5] ; Paul A,van Leeuwen ^[6]

作者单位： Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. n.buijs@vumc.nl. ^[1] Department of Surgery, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands. n.buijs@vumc.nl. ^[2] Department of Surgery, Medical Center Alkmaar, Trial Center Holland Health, Alkmaar, The Netherlands. n.buijs@vumc.nl. ^[3] Department of Pediatrics, Academic Medical Center, Emma Children's Hospital, Amsterdam, The Netherlands. ^[4] Department of Cell Biology and Physiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. ^[5] Department of Surgery, Medical Center Alkmaar, Trial Center Holland Health, Alkmaar, The Netherlands. ^[6] Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. ^[7] Department of Surgery, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands. ^[8]

关键词 Angiogenesis Arginine Asymmetric dimethylarginine Dimethylarginine dimethylaminohydrolase Hepatocellular carcinoma Hypoxia Nitric oxide VEGF