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首页> Protein & cell> Single-cell transcriptomics reveals gene signatures and alterations associated with aging in distinct neural stem/progenitor cell subpopulations.

Single-cell transcriptomics reveals gene signatures and alterations associated with aging in distinct neural stem/progenitor cell subpopulations.

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作者： Zhanping,Shi ^[1] ; Yanan,Geng ^[1] ; Jiping,Liu ^[1] ; Huina,Zhang ^[1] ; Liqiang,Zhou ^[1] ; Quan,Lin ^[1] ; Juehua,Yu ^[2] ; Kunshan,Zhang ^[1] ; Jie,Liu ^[1] ; Xinpei,Gao ^[1] ; Chunxue,Zhang ^[1] ; Yinan,Yao ^[1] ; Chong,Zhang ^[1] ; Yi E,Sun ^[1]

作者单位： Stem Cell Translational Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China. ^[1] Department of Psychiatry and Biobehavioral Sciences and Intellectual Development and Disabilities Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA. ^[2] Stem Cell Translational Research Center, Tongji Hospital, Tongji University School of Medicine, Shanghai, 200065, China. yi.eve.sun@gmail.com. ^[3] Department of Psychiatry and Biobehavioral Sciences and Intellectual Development and Disabilities Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA. yi.eve.sun@gmail.com. ^[4] Collaborative Innovation Center for Brain Science, Tongji University, Shanghai, 200092, China. yi.eve.sun@gmail.com. ^[5]

关键词 Erk1/2 NSC/NPCs SEZ/SVZ aging cell cycle single cell transcriptome

主题词衰老(Aging);动物(Animals);星形细胞(Astrocytes);脑(Brain);细胞分化(Cell Differentiation);细胞分裂(Cell Division);细胞增殖(Cell Proliferation);基因表达调控(Gene Expression Regulation);小鼠(Mice);神经干细胞(Neural Stem Cells);单细胞分析(Single-Cell Analysis);干细胞(Stem Cells)

DOI 10.1007/s13238-017-0450-2

PMID 28748452

发布时间 2019-02-25

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Protein & cell

Protein & cell

2018年9卷4期

351-364页

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Protein & cell

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Protein & cell

2018年9卷4期

351-364页

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