Metabolic Profiling of CB1 Neutral Antagonists.

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第一作者： Herbert H,Seltzman

第一单位： Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, United States. Electronic address: hhs@rti.org.

作者： Herbert H,Seltzman ^[1] ; Rangan,Maitra ^[2] ; Katharine,Bortoff ^[3] ; Jay,Henson ^[4] ; Patricia H,Reggio ^[5] ; Daniel,Wesley ^[6] ; Joseph,Tam ^[7]

作者单位： Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, United States. Electronic address: hhs@rti.org. ^[1] Center for Drug Discovery, Research Triangle Institute, Research Triangle Park, NC, United States. ^[2] Bioagilytix, Durham, NC, United States. ^[3] QuintilesIMS, RTP, NC, United States. ^[4] University of North Carolina at Greensboro, Greensboro, NC, United States. ^[5] Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, MD, United States. ^[6] Obesity and Metabolism Laboratory, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. ^[7]

关键词 Alcoholic steatosis CB1R Glycemic control Metabolic syndrome effects Modeling Neutral antagonist Obesity PIMSR