换一批
换一批Brachyury gene copy number gain and activation of the PI3K/Akt pathway: association with upregulation of oncogenic Brachyury expression in skull base chordoma.
作者：
关键词
DMSO = dimethyl sulfoxideEMT = epithelial-mesenchymal transitionFC = fold changeKEGG = Kyoto Encyclopedia of Genes and GenomesPFS = progression-free survivalPI3K/Akt pathwaybrachyurycDNA = complementary DNAchordomacopy numberhESC = human embryonic stem cellmTOR = mammalian target of rapamycinoncologyqRT-PCR = quantitative real-time reverse transcription polymerase chain reactionskull base
主题词
成年人(Adult);老年人(Aged);细胞系, 肿瘤(Cell Line, Tumor);脊索瘤(Chordoma);女(雌)性(Female);胎儿蛋白质类(Fetal Proteins);基因剂量(Gene Dosage);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);中年人(Middle Aged);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);RNA, 信使(RNA, Messenger);信号传导(Signal Transduction);颅底肿瘤(Skull Base Neoplasms);T盒域蛋白质类(T-Box Domain Proteins);增量调节(Up-Regulation)
DOI
10.3171/2016.12.JNS161444
PMID
28753115
发布时间
2022-03-30
- 浏览148
Journal of neurosurgery
1428-1437页
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