Immunogenetic Profiling for Gastric Cancers Identifies Sulfated Glycosaminoglycans as Major and Functional B Cell Antigens in Human Malignancies.

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作者： Hiroto,Katoh ^[1] ; Daisuke,Komura ^[1] ; Hiroki,Konishi ^[1] ; Ryohei,Suzuki ^[1] ; Asami,Yamamoto ^[1] ; Miwako,Kakiuchi ^[2] ; Reiko,Sato ^[1] ; Tetsuo,Ushiku ^[3] ; Shogo,Yamamoto ^[2] ; Kenji,Tatsuno ^[2] ; Takashi,Oshima ^[4] ; Sachiyo,Nomura ^[5] ; Yasuyuki,Seto ^[5] ; Masashi,Fukayama ^[3] ; Hiroyuki,Aburatani ^[2] ; Shumpei,Ishikawa ^[6]

作者单位： Department of Genomic Pathology, Medical Research Institute, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan. ^[1] Genome Science Division, Research Center for Advanced Science and Technology, University of Tokyo, 153-0041 Tokyo, Japan. ^[2] Department of Pathology, Graduate School of Medicine, University of Tokyo, 113-0033 Tokyo, Japan. ^[3] Department of Surgery, Yokohama City University, 236-0027 Kanagawa, Japan. ^[4] Department of Gastrointestinal Surgery, Graduate School of Medicine, University of Tokyo, 113-0033 Tokyo, Japan. ^[5] Department of Genomic Pathology, Medical Research Institute, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan. Electronic address: sish.gpat@mri.tmd.ac.jp. ^[6]

关键词 gastric cancer immunogenetics repertoire sequence sulfated glycosaminoglycan therapeutic antibody tumor immunity tumor-infiltrating B cell