MMP-13 deletion decreases profibrogenic molecules and attenuates N-nitrosodimethylamine-induced liver injury and fibrosis in mice.
作者:
主题词
肌动蛋白类(Actins);丙氨酸转氨酶(Alanine Transaminase);动物(Animals);天冬氨酸氨基转移酶类(Aspartate Aminotransferases);胶原Ⅰ型(Collagen Type I);结缔组织生长因子(Connective Tissue Growth Factor);二甲基亚硝胺(Dimethylnitrosamine);女(雌)性(Female);基因表达调控(Gene Expression Regulation);肝星状细胞(Hepatic Stellate Cells);透明质酸(Hyaluronic Acid);注射, 腹腔内(Injections, Intraperitoneal);肝(Liver);肝硬化(Liver Cirrhosis);男(雄)性(Male);基质金属蛋白酶13(Matrix Metalloproteinase 13);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);信号传导(Signal Transduction);转化生长因子β1(Transforming Growth Factor beta1)
DOI
10.1111/jcmm.13304
PMID
28782260
发布时间
2019-12-10
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