A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells.
第一作者:
Leigh,Atchison
第一单位:
Department of Biomedical Engineering at Duke University, Durham, NC, 27708, United States.
作者:
主题词
动物(Animals);血管(Blood Vessels);细胞分化(Cell Differentiation);疾病模型, 动物(Disease Models, Animal);成纤维细胞(Fibroblasts);基因表达(Gene Expression);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);核纤层蛋白A型(Lamin Type A);突变(Mutation);肌细胞, 平滑肌(Myocytes, Smooth Muscle);表型(Phenotype);早衰(Progeria);西罗莫司(Sirolimus);组织工程(Tissue Engineering)
DOI
10.1038/s41598-017-08632-4
PMID
28811655
发布时间
2024-07-18
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