首页> Nature communications> Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes.

Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes.

导出 OA

翻译打印收藏纠错

第一作者： Vagheesh M,Narasimhan

第一单位： Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. vagheesh@mail.harvard.edu.

作者： Vagheesh M,Narasimhan ^[1] ; Raheleh,Rahbari ^[2] ; Aylwyn,Scally ^[3] ; Arthur,Wuster ^[4] ; Dan,Mason ^[5] ; Yali,Xue ^[2] ; John,Wright ^[5] ; Richard C,Trembath ^[6] ; Eamonn R,Maher ^[7] ; David A,van Heel ^[8] ; Adam,Auton ^[9] ; Matthew E,Hurles ^[2] ; Chris,Tyler-Smith ^[2] ; Richard,Durbin ^[2]

作者单位： Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. vagheesh@mail.harvard.edu. ^[1] Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. ^[2] Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK. ^[3] Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.;Department of Human Genetics and Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA, 94080, USA. ^[4] Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, BD9 6RJ, UK. ^[5] Division of Genetics and Molecular Medicine, Faculty of Life Sciences and Medicine, King's College, London, SE1 1UL, UK. ^[6] Department of Medical Genetics, University of Cambridge, Cambridge, CB2 0QQ, UK.;Cambridge NIHR Biomedical Research Centre, Cambridge, CB2 0QQ, UK. ^[7] Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, UK. ^[8] Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. ^[9]