Contribution of Intrinsic Lactate to Maintenance of Seizure Activity in Neocortical Slices from Patients with Temporal Lobe Epilepsy and in Rat Entorhinal Cortex.

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作者： Eskedar Ayele,Angamo ^[1] ; Rizwan,ul Haq ^[2] ; Jörg,Rösner ^[3] ; Siegrun,Gabriel ^[4] ; Zoltán,Gerevich ^[5] ; Uwe,Heinemann ^[6] ; Richard,Kovács ^[7]

作者单位： Neuroscience Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. eskedar.angamo@charite.de. ^[1] Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. eskedar.angamo@charite.de. ^[2] Department of Pharmaceutical Sciences, Abbottabad University of Sciences and Technology, Abbottabad 22500, Pakistan. rizwanhej@gmail.com. ^[3] Neuroscience Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. joerg.roesner@charite.de. ^[4] Neuroscience Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. siegrun.gabriel@charite.de. ^[5] Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. zoltan.gerevich@charite.de. ^[6] Neuroscience Research Center, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. mozsafa@gmail.com. ^[7] Institute for Neurophysiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Charitéplatz 1, 10117 Berlin, Germany. richard.kovacs@charite.de. ^[8]

关键词 adenosine interictal activity lactate mesial temporal lobe epilepsy monocarboxylate transporter inhibitors seizure