Opioid Tripeptides Hybridized with trans-1-Cinnamylpiperazine as Proliferation Inhibitors of Pancreatic Cancer Cells in Two- and Three-Dimensional in vitro Models.

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第一作者： Anna K,Laskowska

第一单位： Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.

作者： Anna K,Laskowska ^[1] ; Anna K,Puszko ^[2] ; Piotr,Sosnowski ^[1] ; Krzysztof,Różycki ^[3] ; Piotr,Kosson ^[4] ; Joanna,Matalińska ^[1] ; Marek,Durlik ^[5] ; Aleksandra,Misicka ^[6]

作者单位： Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland. ^[1] Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. ^[2] Laboratory of Chemical Synthesis, CePT, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland. ^[3] Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.;Toxicology Research Laboratory, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland. ^[4] Department of Surgical Research and Transplantology, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.;Department of Gastroenterology and Transplantology, Central Clinical Hospital of the Ministry of the Internal Affairs in Warsaw, Wołoska 137, 02-507, Warsaw, Poland. ^[5] Department of Neuropeptides, Mossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.;Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. ^[6]

关键词 anticancer drugs opioid receptors pancreatic cancer peptidomimetics spheroids