Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy.-论文-万方医学网

第一作者： Rüdiger,Klapdor

第一单位： 1 Department of Gynecology and Obstetrics, Hannover Medical School , Hannover, Germany .

作者： Rüdiger,Klapdor ^[1] ; Shuo,Wang ^[2] ; Ulrich,Hacker ^[3] ; Hildegard,Büning ^[1] ; Michael,Morgan ^[2] ; Thilo,Dörk ^[2] ; Peter,Hillemanns ^[4] ; Axel,Schambach ^[2]

作者单位： 1 Department of Gynecology and Obstetrics, Hannover Medical School , Hannover, Germany . ^[1] 2 Institute for Experimental Hematology, Hannover Medical School , Hannover, Germany . ^[2] 3 Cluster of Excellence REBIRTH, Hannover Medical School , Hannover, Germany . ^[3] 4 University Cancer Center Leipzig (UCCL), University Hospital Leipzig , Leipzig, Germany . ^[4] 5 Division of Hematology/Oncology, Boston Children's Hospital , Harvard Medical School, Boston, Massachusetts. ^[5]

主题词动物(Animals);抗体亲和力(Antibody Affinity);抗原, 肿瘤(Antigens, Neoplasm);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞毒性, 免疫(Cytotoxicity, Immunologic);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因表达(Gene Expression);基因顺序(Gene Order);遗传载体(Genetic Vectors);人类(Humans);免疫疗法(Immunotherapy);慢病毒属(Lentivirus);小鼠(Mice);肿瘤干细胞(Neoplastic Stem Cells);卵巢肿瘤(Ovarian Neoplasms);蛋白质结合(Protein Binding);受体, 抗原(Receptors, Antigen);重组融合蛋白质类(Recombinant Fusion Proteins);单链抗体(Single-Chain Antibodies);转导, 遗传(Transduction, Genetic);转基因(Transgenes);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1089/hum.2017.168

PMID 28836469

发布时间 2018-09-07

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Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy.

Human gene therapy

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Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy.

Human gene therapy

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Human gene therapy

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