In vitro assessment of anti-tumorigenic mechanisms and efficacy of NanoALA, a nanoformulation of aminolevulic acid designed for photodynamic therapy of cancer.

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作者： Laise Rodrigues,de Andrade ^[1] ; Fernando Lucas,Primo ^[2] ; Jaqueline Rodrigues,da Silva ^[3] ; Antonio Claudio,Tedesco ^[4] ; Zulmira Guerrero Marques,Lacava ^[5]

作者单位： University of Brasília, Institute of Biological Sciences, Center of Nanoscience and Nanobiotechnology, 70910-900, Brasilia, DF, Brazil. Electronic address: laisedeandrade@hotmail.com. ^[1] São Paulo State University (UNESP), School of Pharmaceutical Sciences, 14801-903, Araraquara, SP, Brazil. Electronic address: flprimo@fcfar.unesp.br. ^[2] University of Brasília, Institute of Biological Sciences, Center of Nanoscience and Nanobiotechnology, 70910-900, Brasilia, DF, Brazil. Electronic address: sol.jaque@gmail.com. ^[3] Department of Chemistry, Center of Nanotechnology and Tissue Engineering - Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, 14010-100, Ribeirão Preto, Brazil. Electronic address: atedesco@usp.br. ^[4] University of Brasília, Institute of Biological Sciences, Center of Nanoscience and Nanobiotechnology, 70910-900, Brasilia, DF, Brazil. Electronic address: zulmira@unb.br. ^[5]

关键词 Aminolevulic-acid (ALA)Mammary carcinoma Nanocarriers Photodynamic therapy (PDT)Poly(lactide-co-glycolide) (PLGA)