Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription.
第一作者:
Tsuyoshi,Hayashi
第一单位:
Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642, USA.
作者:
医学主题词
抗HIV药(Anti-HIV Agents);细胞系(Cell Line);药物批准(Drug Approval);药物发现(Drug Discovery);基因表达调控, 病毒(Gene Expression Regulation, Viral);HIV感染(HIV Infections);HIV长末端重复序列(HIV Long Terminal Repeat);HIV-1(HIV-1);人类(Humans);腙类(Hydrazones);哒嗪类(Pyridazines);小分子化合物库(Small Molecule Libraries);转录, 遗传(Transcription, Genetic);病毒激活(Virus Activation);病毒潜伏期(Virus Latency)
DOI
10.1016/j.antiviral.2017.08.013
PMID
28842263
发布时间
2019-02-28
- 浏览5
Antiviral research
76-85页
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