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CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression.

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第一作者: Yongqing,Liu
第一单位: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China.
作者: Yongqing,Liu [1] ; Shirong,Lai [2] ; Weining,Ma [1] ; Wei,Ke [2] ; Chan,Zhang [3] ; Shumeng,Liu [4] ; Yu,Zhang [5] ; Fei,Pei [1] ; Shaoyi,Li [1] ; Ming,Yi [6] ; Yousheng,Shu [3] ; Yongfeng,Shang [5] ; Jing,Liang [4] ; Zhuo,Huang [1]
作者单位: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China. [1] Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, 100191, China. [2] Department of Neurology, Shengjing Hospital Affiliated to China Medical University, Shenyang, 110000, China. [3] State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, School of Brain and Cognitive Sciences, the Collaborative Innovation Center for Brain Science, Beijing Normal University, Beijing, 100875, China. [4] Neuroscience Research Institute & Department of Neurobiology, Peking University Health Science Center, Beijing, 100191, China. [5] Department of Pathology, Peking University Health Science Center, Beijing, 100191, China. [6] Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China. [7] Department of Biochemistry and Molecular Biology, Tianjin Medical University, Tianjin, 300070, China. [8] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China. liang_jing@bjmu.edu.cn. [9] Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China. huangz@hsc.pku.edu.cn. [10] Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, 100191, China. huangz@hsc.pku.edu.cn. [11] State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. huangz@hsc.pku.edu.cn. [12]
DOI 10.1038/s41467-017-00368-z
PMID 28842554
发布时间 2020-12-09
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