CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression.
第一作者:
Yongqing,Liu
第一单位:
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), State Key Laboratory of Natural and Biomimetic Drugs, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China.
作者:
主题词
动物(Animals);辅阻遏蛋白质类(Co-Repressor Proteins);癫痫(Epilepsy);基因表达调控(Gene Expression Regulation);基因敲低技术(Gene Knockdown Techniques);海马(Hippocampus);组蛋白酰基转移酶(Histone Acetyltransferases);人类(Humans);氢裂合酶类(Hydro-Lyases);离子通道闸门(Ion Channel Gating);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);神经元可塑性(Neuronal Plasticity);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);发作(Seizures)
DOI
10.1038/s41467-017-00368-z
PMID
28842554
发布时间
2020-12-09
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