Capture of anti-coagulant active ingredients from Moutan Cortex by platelet immobilized chromatography and evaluation of anticoagulant activity in rats.

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作者： Huihui,Qiu ^[1] ; Li,Zhang ^[2] ; Maomao,Zhu ^[3] ; Minghua,Zhang ^[4] ; Juan,Chen ^[1] ; Liang,Feng ^[5] ; Xiaobin,Jia ^[6] ; Joe Antony,Jacob ^[7]

作者单位： Nanjing University of Chinese Medicine, Nanjing 210023, PR China; Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China. ^[1] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China; Jiangsu University, Zhenjiang 212013, PR China. ^[2] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China; Nanjing Institute of Product Quality Inspection, Nanjing 210028, PR China. ^[3] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China. ^[4] Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China. Electronic address: wenmoxiushi@163.com. ^[5] Nanjing University of Chinese Medicine, Nanjing 210023, PR China; Key Laboratory of New Drug Delivery System of Chinese Materia Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, PR China. Electronic address: jxiaobin2005@hotmail.com. ^[6] Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, PR China. ^[7]

关键词 Anti-coagulant HPLC–MS/MS Moutan Cortex Platelet immobilized chromatography