Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors: a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia?

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作者： Mario,Herrera-Marschitz ^[1] ; Ronald,Perez-Lobos ^[2] ; Carolyne,Lespay-Rebolledo ^[3] ; Andrea,Tapia-Bustos ^[2] ; Emmanuel,Casanova-Ortiz ^[2] ; Paola,Morales ^[2] ; Jose-Luis,Valdes ^[2] ; Diego,Bustamante ^[4] ; Bruce K,Cassels ^[4]

作者单位： Programme of Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Av. Independencia, PO Box 8389100, 1027, Santiago, Chile. mh-marschitz@med.uchile.cl. ^[1] Programme of Molecular & Clinical Pharmacology, ICBM, Faculty of Medicine, University of Chile, Av. Independencia, PO Box 8389100, 1027, Santiago, Chile. ^[2] Escuela de Tecnologia Medica, Facultad de Medicina, Universidad Andres Bello, PO Box 8370146, Santiago, Chile. ^[3] Faculty of Sciences, University of Chile, Santiago, Chile. ^[4] Department of Neuroscience, Faculty of Medicine, University of Chile, Santiago, Chile. ^[5]

关键词 Basal ganglia Delayed cell death GFAP Hypoxic ischaemic encephalopathy (HIE)Leukomalacia MAP-2 Memantine Neonatal hypoxia Niacinamide Organotypic cultures Rat TUNEL nNOS