换一批Celecoxib normalizes the tumor microenvironment and enhances small nanotherapeutics delivery to A549 tumors in nude mice.
第一作者：
Bo,Zhang
第一单位：
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, PR China.
作者：
医学主题词
腺癌, 细支气管肺泡(Adenocarcinoma, Bronchiolo-Alveolar);动物(Animals);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);用药计划表(Drug Administration Schedule);药物释放系统(Drug Delivery Systems);药物协同作用(Drug Synergism);药物疗法, 联合(Drug Therapy, Combination);基因表达(Gene Expression);人类(Humans);肺肿瘤(Lung Neoplasms);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);微胶粒(Micelles);纳米粒子(Nanoparticles);新生血管化, 病理性(Neovascularization, Pathologic);紫杉酚(Paclitaxel);多酯类(Polyesters);聚乙烯二醇类(Polyethylene Glycols);肿瘤负荷(Tumor Burden);肿瘤微环境(Tumor Microenvironment);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1038/s41598-017-09520-7
PMID
28855534
发布时间
2019-04-23
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