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首页> PloS one> Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes.

Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes.

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作者： Julius O,Nyalwidhe ^[1] ; Wojciech J,Grzesik ^[2] ; Tanya C,Burch ^[3] ; Michele L,Semeraro ^[1] ; Tayab,Waseem ^[2] ; Ivan C,Gerling ^[3] ; Raghavendra G,Mirmira ^[1] ; Margaret A,Morris ^[4] ; Jerry L,Nadler ^[5]

作者单位： Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, Virginia, United States of America. ^[1] Leroy T. Canoles Jr. Cancer Research Center, Eastern Virginia Medical School, Norfolk, Virginia, United States of America. ^[2] Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, Virginia, United States of America. ^[3] Division of Endocrinology, Diabetes and Metabolism, The University of Tennessee Health Science Center, Memphis, Tennessee, United States of America. ^[4] Department of Pediatrics, Center for Diabetes and Metabolic Diseases, Indiana University, Indianapolis, Indiana, United States of America. ^[5] The Strelitz Diabetes Center, Eastern Virginia Medical Center, Norfolk, Virginia, United States of America. ^[6]

主题词成年人(Adult);儿童(Child);色谱法, 液相(Chromatography, Liquid);糖尿病, 1型(Diabetes Mellitus, Type 1);女(雌)性(Female);人类(Humans);胰岛(Islets of Langerhans);男(雄)性(Male);质谱分析法(Mass Spectrometry);代谢网络和途径(Metabolic Networks and Pathways);显微镜检查, 共焦(Microscopy, Confocal);显微镜检查, 荧光(Microscopy, Fluorescence);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs);蛋白质组学(Proteomics);青年人(Young Adult)

DOI 10.1371/journal.pone.0183908

PMID 28877242

发布时间 2024-03-26

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PloS one

PloS one

2017年12卷9期

e0183908页

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