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首页> BMC nephrology> Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition.

Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition.

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作者： Luiz Henrique Gomes,Matheus ^[1] ; Gislene Mendes,Simão ^[1] ; Taíssa Altieri,Amaral ^[1] ; Rodrigo Barbosa Oliveira,Brito ^[1] ; Camila Soares,Malta ^[1] ; Yves Silva Teles,Matos ^[1] ; Alexandre Chagas,Santana ^[1] ; Gabriela Gomes Cardoso,Rodrigues ^[1] ; Maria Clara,Albejante ^[1] ; Erna Elisabeth,Bach ^[1] ; Maria Aparecida,Dalboni ^[1] ; Cleber Pinto,Camacho ^[1] ; Humberto,Dellê ^[2]

作者单位： Postgraduate Program in Medicine, Universidade Nove de Julho (UNINOVE), Rua Vergueiro, 235, 2º subsolo, São Paulo, 01504-001, São Paulo, Brazil. ^[1] Postgraduate Program in Medicine, Universidade Nove de Julho (UNINOVE), Rua Vergueiro, 235, 2º subsolo, São Paulo, 01504-001, São Paulo, Brazil. hdelle@usp.br. ^[2]

关键词 1-methyl-D-tryptophan Epithelial to mesenchymal transition Indoleamine 2, 3-dioxygenase Renal fibrosis Renal inflammation TGF-β 1

主题词动物(Animals);狗(Dogs);上皮-间质转化(Epithelial-Mesenchymal Transition);纤维化(Fibrosis);吲哚胺-吡咯2,3-双加氧酶(Indoleamine-Pyrrole 2,3,-Dioxygenase);肾疾病(Kidney Diseases);男(雄)性(Male);大鼠(Rats);大鼠, Wistar(Rats, Wistar);转化生长因子β1(Transforming Growth Factor beta1);色氨酸(Tryptophan)

DOI 10.1186/s12882-017-0702-7

PMID 28877670

发布时间 2019-01-09

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BMC nephrology

BMC nephrology

2017年18卷1期

287页

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