Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model.

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作者： Colette A,Bichsel ^[1] ; Limei,Wang ^[2] ; Laurène,Froment ^[3] ; Sabina,Berezowska ^[4] ; Stefan,Müller ^[3] ; Patrick,Dorn ^[5] ; Thomas M,Marti ^[3] ; Ren-Wang,Peng ^[5] ; Thomas,Geiser ^[6] ; Ralph A,Schmid ^[7] ; Olivier T,Guenat ^[3] ; Sean R R,Hall ^[5]

作者单位： ARTORG Organs-on-Chip Technologies, University of Bern, Bern, Switzerland. ^[1] Department of Pulmonary Medicine, Inselspital, Bern University Hospital, Bern, Switzerland. ^[2] Department of BioMedical Research, University of Bern, Bern, Switzerland. ^[3] Vascular Biology Program, Boston Children's Hospital, Boston, MA, USA. ^[4] Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland. ^[5] Department of Pathology, University of Bern, Bern, Switzerland. ^[6] Flow cytometry core facility, Department of BioMedical Research, University of Bern, Bern, Switzerland. ^[7] Department of BioMedical Research, University of Bern, Bern, Switzerland. Ralph.Schmid@insel.ch. ^[8] Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland. Ralph.Schmid@insel.ch. ^[9] Department of BioMedical Research, University of Bern, Bern, Switzerland. Sean.Hall@insel.ch. ^[10] Division of General Thoracic Surgery, Inselspital, Bern University Hospital, Bern, Switzerland. Sean.Hall@insel.ch. ^[11]